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DSPE-PEG8-Mal

DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2112737-94-5]

UNSPSC

12352200

Hazard Statement

H302-H315-H319-H335

Target

Liposome; PROTAC Linkers

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dspe-peg8-mal.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(C=CC1=O)=O)=O)(O)=O)=O

Molecular Formula

C64H119N2O19P

Molecular Weight

1251.61

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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