M-PEG8-DSPE
M-PEG8-DSPE is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
UNSPSC
12352200
Hazard Statement
H302-H315-H319-H335
Target
Liposome; PROTAC Linkers
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg8-dspe.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCCCC(OCC(COP(OCCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)(O)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O
Molecular Formula
C59H116NO17P
Molecular Weight
1142.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Curated Selection
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