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N- (Biotin) -N-bis (PEG1-alcohol)

N- (Biotin) -N-bis (PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2100306-75-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-biotin-n-bis-peg1-alcohol.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CCOCCO)CCOCCO)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O

Molecular Formula

C18H33N3O6S

Molecular Weight

419.54

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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