TAMRA-Azide-PEG-biotin

TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640) . TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[1797415-74-7]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tamra-azide-peg-biotin.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN(C)C1=CC([O+]=C(C=C(N(C)C)C=C2)C2=C3C4=CC=C(C(NCCC(N(CCC(NCCOCCOCCOCCNC(CCCCC5SC(NC(N6)=O)C6C5)=O)=O)CCOCCOCCOCCN=[N+]=[N-])=O)=O)C=C4C([O-])=O)=C3C=C1.CN(C)C7=CC([O+]=C(C=C(N(C)C)C=C8)C8=C9C%10=CC(C(NCCC(N(CCC(NCCOCCOCCOCCNC(CCCCC%11SC(NC(N%12)=O)C%12C%11)=O)=O)CCOCCOCCOCCN=[N+]=[N-])=O)=O)=CC=C%10C([O-])=O)=C9C=C7

Molecular Formula

C57H79N11O14S

Molecular Weight

1174.38

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562|[2]Zhang X, et al. CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism. Cell Rep. 2024 Sep 24;43 (9) :114662.