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Biotin-PEG7-thiourea

Biotin-PEG7-thiourea is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

2353409-59-1

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-peg7-thiourea.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOCCOCCOCCOCCOCCOCCOCCNC(N)=S)CCCC[C@H]1[C@](NC2=O)([H])[C@](N2)([H])CS1

Molecular Formula

C27H51N5O9S2

Molecular Weight

653.85

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13 (5) :514-521.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Frequently Asked Questions

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