Boc-N-Amido-PEG3-azide
Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-N-Amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-n-amido-peg3-azide.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)NCCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C13H26N4O5
Molecular Weight
318.37
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140835/Boc-N-Amido-PEG3-azide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140835/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
CAS Number
[642091-68-7]
Available Sizes
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USP33, CT (Ubiquitin Carboxyl-terminal Hydrolase 33, Ubiquitin Thiolesterase 33, Ubiquitin-specific Processing Protease 33, Deubiquitinating Enzyme 33, VHL-interacting Deubiquitinating Enzyme 1, hVDU1, KIAA1097, VDU1) (FITC)