Azide-PEG6-amido-C16-Boc

Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

Product Name Alternative

17- (Azide-PEG6-ethylcarbamoyl) heptadecanoic t-butyl ester

UNSPSC

12352211

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/azide-peg6-amido-c16-boc.html

Solubility

10 mM in DMSO

Smiles

CC(C)(C)OC(CCCCCCCCCCCCCCCCC(NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O

Molecular Formula

C36H70N4O9

Molecular Weight

702.96

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562