Dioxoisoindolin-O-PEG-OH (MW 2000)

Dioxoisoindolin-O-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

Product Name Alternative

(1,3-dioxoisoindolin-2-yl) -O-PEG-OH (MW 2000)

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dioxoisoindolin-o-peg-oh-mw-2000.html

Solubility

10 mM in DMSO

Smiles

O=C1N(OCCOCCO)C(C2=C1C=CC=C2)=O.[n]

Molecular Weight

2000 (Average)

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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