N- (DBCO-PEG4) -N-Biotin-PEG4-NHS
N- (DBCO-PEG4) -N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (DBCO-PEG4) -N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
2353409-72-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-dbco-peg4-n-biotin-peg4-nhs.html
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN(C(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O)CCOCCOCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O
Molecular Formula
C54H74N6O16S
Molecular Weight
1095.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Frequently Asked Questions
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