NH-bis (C2-PEG1-azide)
NH-bis (C2-PEG1-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH-bis (C2-PEG1-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
2100306-81-6
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh-bis-c2-peg1-azide.html
Purity
99.87
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NCCOCCNCCOCCN=[N+]=[N-]
Molecular Formula
C8H17N7O2
Molecular Weight
243.27
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Frequently Asked Questions
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