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N-Mal-N-bis (PEG2-acid)

N-Mal-N-bis (PEG2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2110449-02-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-mal-n-bis-peg2-acid.html

Purity

96.0

Solubility

10 mM in DMSO

Smiles

O=C(O)CCOCCOCCN(C(CCN1C(C=CC1=O)=O)=O)CCOCCOCCC(O)=O

Molecular Formula

C21H32N2O11

Molecular Weight

488.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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