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1,3-bis (carboxyethoxy) -2,2-bis (carboxyethoxy) propane

1,3-bis (carboxyethoxy) -2,2-bis (carboxyethoxy) propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

35638-19-8

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-3-bis-carboxyethoxy-2-2-bis-carboxyethoxy-propane.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(CCOCC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O)O

Molecular Formula

C17H28O12

Molecular Weight

424.40

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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