1,3-bis (carboxyethoxy) -2,2-bis (carboxyethoxy) propane
1,3-bis (carboxyethoxy) -2,2-bis (carboxyethoxy) propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[35638-19-8]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-3-bis-carboxyethoxy-2-2-bis-carboxyethoxy-propane.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(CCOCC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O)O
Molecular Formula
C17H28O12
Molecular Weight
424.40
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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