2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane
Product Specifications
UNSPSC Description
2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-azido-peg3-amido-1-3-bis-carboxylethoxy-propane.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCOCC(COCCC(O)=O)NC(CCOCCOCCOCCN=[N+]=[N-])=O
Molecular Weight
464.47
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140522/2-Azido-PEG3-amido-1-3-bis-carboxylethoxy-propane-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140522/
Clinical Information
No Development Reported
CAS Number
2086689-05-4
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