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T-Boc-Aminooxy-PEG12-NHS ester

T-Boc-Aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/t-boc-aminooxy-peg12-nhs-ester.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)NOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

Molecular Formula

C36H66N2O19

Molecular Weight

830.91

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

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