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Tos-PEG8-Tos

Tos-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[57436-38-1]

UNSPSC

12352005

Hazard Statement

H315-H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tos-peg8-tos.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCCOCCOCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O

Molecular Formula

C30H46O13S2

Molecular Weight

678.81

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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