Bis-Tos-PEG6

Bis-Tos-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[42749-27-9]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-tos-peg6.html

Purity

98.91

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O

Molecular Formula

C26H38O11S2

Molecular Weight

590.70

Precautions

H315, H319

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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