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Tos-PEG5-CH2COOtBu

Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[1949793-62-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tos-peg5-ch2cootbu.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)COCCOCCOCCOCCOCCOS(=O)(C1=CC=C(C)C=C1)=O

Molecular Formula

C23H38O10S

Molecular Weight

506.61

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Curated Selection

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