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Fmoc-NH-pentanoic acid-NHS-SO3Na

Fmoc-NH-pentanoic acid-NHS-SO3Na is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fmoc-nh-pentanoic-acid-nhs-so3na.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCCCC(ON4C(CC(C4=O)S(=O)(O[Na])=O)=O)=O

Molecular Formula

C24H23N2NaO9S

Molecular Weight

538.50

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Curated Selection

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