Carboxyrhodamine 110-PEG4-DBCO
Product Specifications
UNSPSC Description
Carboxyrhodamine 110-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Carboxyrhodamine 110-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carboxyrhodamine-110-peg4-dbco.html
Solubility
10 mM in DMSO
Smiles
[O-]C(C1=C(C2=C3C=CC(C=C3OC4=C2C=CC(N)=C4)=[NH2+])C=C(C(NCCOCCOCCOCCOCCC(NCCC(N5C6=C(C#CC7=C(C5)C=CC=C7)C=CC=C6)=O)=O)=O)C=C1)=O.[O-]C(C8=C(C(C9=C(O%10)C=C(N)C=C9)=C(C=C%11)C%10=CC%11=[NH2+])C=CC(C(NCCOCCOCCOCCOCCC(NCCC(N%12C%13=C(C#CC%14=C(C%12)C=CC=C%14)C=CC=C%13)=O)=O)=O)=C8)=O
Molecular Weight
879.97
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140297/Carboxyrhodamine-110-PEG4-DBCO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140297/
Clinical Information
No Development Reported
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