N- (Amino-PEG1) -N-bis (PEG2-propargyl)
N- (Amino-PEG1) -N-bis (PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (Amino-PEG1) -N-bis (PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2100306-47-4]
UNSPSC
12352211
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-amino-peg1-n-bis-peg2-propargyl.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
NCCOCCN(CCOCCOCC#C)CCOCCOCC#C
Molecular Formula
C18H32N2O5
Molecular Weight
356.46
References & Citations
[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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