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Aminooxy-PEG3-propargyl

Aminooxy-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aminooxy-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1807537-27-4]

UNSPSC

12352211

Hazard Statement

H227, H302, H312, H315, H318, H332, H335, H412

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aminooxy-peg3-propargyl.html

Purity

98.0

Solubility

DMSO : ≥ 250 mg/mL

Smiles

NOCCOCCOCCOCC#C

Molecular Formula

C9H17NO4

Molecular Weight

203.24

Precautions

H227, H302, H312, H315, H318, H332, H335, H412

References & Citations

[1]Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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