Bis-propargyl-O-PEG17
Product Specifications
UNSPSC Description
Bis-propargyl-O-PEG17 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-propargyl-O-PEG17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-propargyl-o-peg17.html
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCC#C.[17]
Molecular Weight
138.16
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140042/Bis-propargyl-O-PEG17-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140042/
Clinical Information
No Development Reported
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