Bis-propargyl-O-PEG17

Bis-propargyl-O-PEG17 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-propargyl-O-PEG17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

UNSPSC

12352211

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-propargyl-o-peg17.html

Solubility

10 mM in DMSO

Smiles

C#CCOCCOCC#C.[17]

Molecular Formula

C8H10O2

Molecular Weight

138.16

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562