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(S, E) -TCO2-PEG3-acid

(S) -TCO-PEG3-acid is a click chemistry PEG linker with a terminal carboxylic acid (COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S) -TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product Specifications

UNSPSC

12352211

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-e-tco2-peg3-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOCCOCCOCCC(O)=O)O[C@@H]1/C=C/CCCCC1

Molecular Formula

C18H31NO7

Molecular Weight

373.44

References & Citations

[1]Joshua J Santiana, et al. Multi-layered stimuli responsive DNA micelles for the stepwise controlled release of small molecules. J Mater Chem B. 2022 Sep 28;10 (37) :7518-7526.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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