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Neuraminidase-IN-3

Neuraminidase-IN-3 (compound 23d) is a potent influenza neuraminidase (NA) inhibitor with IC50 values of 0.73, 0.26, and 0.63 nM against H1N1, H5N1, and H5N8 NAs, respectively[1].

Product Specifications

CAS Number

2699874-41-2

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/neuraminidase-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C1)=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@H]1NCC2=CC(C(C=CC=C3)=C3S4)=C4C=C2

Molecular Formula

C27H32N2O4S

Molecular Weight

480.62

References & Citations

[1]Ju H, et al. Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability. J Med Chem. 2021;64 (24) :17992-18009.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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