VPC-13789
Product Specifications
UNSPSC Description
VPC-13789 is a potent, selective, and orally bioavailable antiandrogen. VPC-13789 can be used for the research of castration-resistant prostate cancer (CRPC) therapeutics. VPC-13789 inhibits androgen receptor (AR) transcriptional activity in LNCaP cells (IC50=0.19 μM)[1].
Target Antigen
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/vpc-13789.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=CC(C3=CNC4=C3C=C(F)C(F)=C4F)=NC2=CC=C1)NC(C)C
Molecular Weight
383.37
References & Citations
[1]Eric Leblanc , et al. Development of 2-(5,6,7-Trifluoro-1 H-Indol-3-yl)-quinoline-5-carboxamide as a Potent, Selective, and Orally Available Inhibitor of Human Androgen Receptor Targeting Its Binding Function-3 for the Treatment of Castration-Resistant Prostate Cancer. J Med Chem. 2021 Oct 28;64(20):14968-14982.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139970/VPC-13789-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139970/
Clinical Information
No Development Reported
CAS Number
2761146-51-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9929627-01 48 Well
Mouse Retinitis Pigmentosa 1-Like 1 Protein (RP1L1) ELISA Kit
Ask
View Details 
MBS9929627-02 96 Well
Mouse Retinitis Pigmentosa 1-Like 1 Protein (RP1L1) ELISA Kit
Ask
View Details MBS9929627-03 5x 96 Well
Mouse Retinitis Pigmentosa 1-Like 1 Protein (RP1L1) ELISA Kit
Ask
View Details 
MBS9929627-04 10x 96 Well
Mouse Retinitis Pigmentosa 1-Like 1 Protein (RP1L1) ELISA Kit
Ask
View Details ![PGP9.5 (UCHL1) Mouse Monoclonal Antibody [Clone ID: OTI6D4]](https://cdn.genprice.uk/genprice/genprice2.png)
