Mal-amido-PEG9-Val-Ala-PAB-SG3200
Mal-amido-PEG9-Val-Ala-PAB-SG3200 is a cleavable ADC linker conjugate used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1817788-75-2]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-amido-peg9-val-ala-pab-sg3200.html
Solubility
10 mM in DMSO
Smiles
O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N3C4=CC(OCCCOC5=C(C=C6C(N=C[C@@]7([H])N(C=C(C7)C)C6=O)=C5)OC)=C(OC)C=C4C(N8[C@](CC(C)=C8)([H])[C@@H]3O)=O)=O)=O)=O)=O)=O
Molecular Formula
C75H101N9O24
Molecular Weight
1512.65
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Curated Selection
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