KRAS G12D inhibitor 7

2648552-34-3

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer

https://www.medchemexpress.com/kras-g12d-inhibitor-7.html

10 mM in DMSO

CN(CCC1)[C@@H]1COC2=NC(N3C[C@@H](N(CC3)C([C@H]4CN4)=O)CC#N)=C5C(CN(C6=CC(O)=CC7=C6C=CC=C7)CC5)=N2

C32H38N8O3

582.70

[1] PITZEN, Jennifer, et al. COVALENT RAS INHIBITORS AND USES THEREOF. Patent WO2021108683A1.

Room temperature

Reference compound1

No Development Reported

K-Ras