XR8-69
Product Specifications
UNSPSC Description
XR8-69 is a SARS-CoV-2 PLpro inhibitor that shows low micromolar antiviral potency in SARS-CoV-2-infected human cells.
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/xr8-69.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C1=CC=CC(C2=CC=C(CNC(C)=O)S2)=C1)C)C3=CC(NC4CNC4)=CC=C3C
Molecular Weight
462.61
References & Citations
[1]Shen Z, et al. Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity. J Med Chem. 2021 Oct 19:acs.jmedchem.1c01307.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139892/XR8-69-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139892/
Clinical Information
No Development Reported
CAS Number
2817811-10-0
Curated Selection
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