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XR8-69

XR8-69 is a SARS-CoV-2 PLpro inhibitor that shows low micromolar antiviral potency in SARS-CoV-2-infected human cells.

Product Specifications

CAS Number

[2817811-10-0]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/xr8-69.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C1=CC=CC(C2=CC=C(CNC(C)=O)S2)=C1)C)C3=CC(NC4CNC4)=CC=C3C

Molecular Formula

C26H30N4O2S

Molecular Weight

462.61

References & Citations

[1]Shen Z, et al. Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity. J Med Chem. 2021 Oct 19:acs.jmedchem.1c01307.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139892/XR8-69-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139892/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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