OXS007417
OXS007417 induces differentiation of acute myeloid leukemia cells (EC50 = 48 nM) in vitro and shows antitumor effects in vivo.
Product Specifications
CAS Number
2761147-94-6
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxs007417.html
Solubility
10 mM in DMSO
Smiles
FC(F)OC(C=C1)=CC=C1N2C=NC3=CN=C(C4=C(C)C=C(F)C=C4)C=C32
Molecular Formula
C20H14F3N3O
Molecular Weight
369.34
References & Citations
[1]Josa-Culleré L, et al. A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo. J Med Chem. 2021 Nov 11;64 (21) :15608-15628.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
44419111 3x 1.0 µg
SMARCE1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details 