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EIF4A3-IN-4

EIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.

Product Specifications

CAS Number

2861994-92-3

UNSPSC

12352005

Target

Eukaryotic Initiation Factor (eIF)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/eif4a3-in-4.html

Purity

99.8

Solubility

10 mM in DMSO

Smiles

OC(C1=C2C(C=CC([N+]([O-])=O)=C2)=NC(C3=CC=C(C4=CC=C(CCCC)C=C4)O3)=C1)=O

Molecular Formula

C24H20N2O5

Molecular Weight

416.43

References & Citations

[1]Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64 (21) :15727-15746.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EIF4

Frequently Asked Questions

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