EIF4A3-IN-4
EIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.
Product Specifications
CAS Number
[2861994-92-3]
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eif4a3-in-4.html
Purity
99.8
Solubility
10 mM in DMSO
Smiles
OC(C1=C2C(C=CC([N+]([O-])=O)=C2)=NC(C3=CC=C(C4=CC=C(CCCC)C=C4)O3)=C1)=O
Molecular Formula
C24H20N2O5
Molecular Weight
416.43
References & Citations
[1]Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64 (21) :15727-15746.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EIF4
Curated Selection
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