Anticancer agent 15
Anticancer agent 15 is capable of significantly increasing the cellular level of ROS and inducing melanoma cancer cell death via necroptosis.
Product Specifications
CAS Number
[2710312-73-3]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-15.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]([C@@H]([C@]1(C)C=C)OC(C2=CC(Cl)=NC(C)=C2)=O)[C@@](CC3=C)(CC[C@H]4C)[C@](C3=O)([H])[C@@]4([C@@H](C1)OC(C5=CC(Cl)=NC(C)=C5)=O)C
Molecular Formula
C35H40Cl2N2O5
Molecular Weight
639.61
References & Citations
[1]Zhang K, et al. A Novel Anticancer Stem Cell Compound Derived from Pleuromutilin Induced Necroptosis of Melanoma Cells. J Med Chem. 2021 Nov 11;64 (21) :15825-15845.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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