TGFβR-IN-1
TGFβR-IN-1 is a long-acting tumor-activated proagent of a TGFβR inhibitor.
Product Specifications
CAS Number
2857845-36-2
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tgfβr-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=C(NC([C@H](CCCCN)NC(CNC([C@@H](NC([C@H](CC(C)C)NC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)C(O)=O)=O)=O)=O)=O)CO)=O)=O)=O)C=C1)NCOCCN2C=NC(C3=CC(Cl)=C(F)C=C3)=C2C(C=C4)=NN5C4=NC=C5C#N
Molecular Formula
C84H121ClFN17O23
Molecular Weight
1791.41
References & Citations
[1]Zhang Y, et al. Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor. J Med Chem. 2021 Nov 11;64 (21) :15787-15798.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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