MK-4688
Product Specifications
UNSPSC Description
MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mk-4688.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](CC1)CC[C@H]1CN(C(N2CCO[C@H]3[C@H]2CCC3)=N4)C5=C4C=C(C(N6)=NOC6=O)N=C5C7=CC(Cl)=CN=C7
Molecular Weight
550.05
References & Citations
[1]Reutershan MH, et al. Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction. J Med Chem. 2021 Nov 11;64(21):16213-16241.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139846/MK-4688-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139846/
Clinical Information
No Development Reported
CAS Number
1616428-79-5
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