Anti-inflammatory agent 6

Anti-inflammatory agent 6 blocks the phosphorylation of I kappa b kinase α/β (IKKα/β), IκBα, and nuclear factor kB p65 (NF-κB p65) which is a key controller of inflammation, thereby showing anti-inflammatory potential.

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

IKK; NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-6.html

Solubility

10 mM in DMSO

Smiles

OC1=C(O)C(O)=C(C(C(OC2OC(C(OC)=O)C(O)C(O)C2O)=C(C3=CC=CC=C3)O4)=O)C4=C1

Molecular Formula

C22H20O12

Molecular Weight

476.39

References & Citations

[1]Sharma N, et al. Dereplication Based Strategy for Rapid Identification and Isolation of a Novel Anti-inflammatory Flavonoid by LCMS/MS from Colebrookea oppositifolia. ACS Omega. 2021 Nov 2;6 (45) :30241-30259.