Anti-inflammatory agent 6
Anti-inflammatory agent 6 blocks the phosphorylation of I kappa b kinase α/β (IKKα/β), IκBα, and nuclear factor kB p65 (NF-κB p65) which is a key controller of inflammation, thereby showing anti-inflammatory potential.
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
IKK; NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-6.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O)C(O)=C(C(C(OC2OC(C(OC)=O)C(O)C(O)C2O)=C(C3=CC=CC=C3)O4)=O)C4=C1
Molecular Formula
C22H20O12
Molecular Weight
476.39
References & Citations
[1]Sharma N, et al. Dereplication Based Strategy for Rapid Identification and Isolation of a Novel Anti-inflammatory Flavonoid by LCMS/MS from Colebrookea oppositifolia. ACS Omega. 2021 Nov 2;6 (45) :30241-30259.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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