Galectin-8-IN-1
Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N), with a Kd of 48 μM and 15-fold selectivity over galectin-3 and even better selectivity over the other mammalian galectins.
Product Specifications
CAS Number
3028946-23-5
UNSPSC
12352005
Target
Galectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/galectin-8-in-1.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](CO)OC=C[C@H]1OCC2=NC3=C(C=C(C(O)=O)C=C3)N2C
Molecular Formula
C16H18N2O6
Molecular Weight
334.32
References & Citations
[1]Hassan M, et al. Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett. 2021 Nov 2;12 (11) :1745-1752.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Galectin-8
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