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Galectin-8-IN-1

Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N), with a Kd of 48 μM and 15-fold selectivity over galectin-3 and even better selectivity over the other mammalian galectins.

Product Specifications

CAS Number

3028946-23-5

UNSPSC

12352005

Target

Galectin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/galectin-8-in-1.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](CO)OC=C[C@H]1OCC2=NC3=C(C=C(C(O)=O)C=C3)N2C

Molecular Formula

C16H18N2O6

Molecular Weight

334.32

References & Citations

[1]Hassan M, et al. Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett. 2021 Nov 2;12 (11) :1745-1752.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Galectin-8

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