PRMT5-IN-11
Product Specifications
UNSPSC Description
PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/prmt5-in-11.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@]([C@H]2O)(CC1)O[C@](N3C4=NC=NC(N)=C4N=C3)([H])[C@@H]2O
Molecular Weight
307.31
References & Citations
[1]Jouffroy L, et al. Regio- and Stereoselective Synthesis of C-4' Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues. Org Lett. 2021 Nov 19;23(22):8828-8833.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139823A/PRMT5-IN-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139823A/
Clinical Information
No Development Reported
CAS Number
2567564-33-2
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