VEGFR-2-IN-10
VEGFR-2-IN-10 exhibits increased antiangiogenic potency (IC50 = 0.7 μM) against VEGF-induced VEGFR2 phosphorylation without cytotoxic effects.
Product Specifications
CAS Number
2760792-40-1
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-10.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(NC3=C2CN(C(CC4=NC=CC=C4)=O)CCC3)C=C1
Molecular Formula
C20H21N3O2
Molecular Weight
335.40
References & Citations
[1]Cho SM, et al. Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact. J Med Chem. 2021 Nov 11;64 (21) :15858-15867.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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