Ticarcillin

Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research[1][2][3].

Product Specifications

CAS Number

[34787-01-4]

UNSPSC

12352005

Hazard Statement

H317-H334

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ticarcillin.html

Solubility

10 mM in DMSO

Smiles

OC([C@H](C1=CSC=C1)C(N[C@H]2[C@]3([H])N(C2=O)[C@H](C(C)(S3)C)C(O)=O)=O)=O

Molecular Formula

C15H16N2O6S2

Molecular Weight

384.43

Precautions

P261-P272-P280-P284-P302+P352-P304+P340-P362+P364-P501

References & Citations

[1]Cecile Formosa, et al. Nanoscale effects of antibiotics on P. aeruginosa. Nanomedicine. 2012 Jan;8 (1) :12-6.|[2]G B van der Voet, et al. Comparison of the antibacterial activity of azlocillin and ticarcillin in vitro and in irradiated neutropenic mice. J Antimicrob Chemother. 1985 Nov;16 (5) :605-13.|[3]Oriel Spierer, et al. Comparative activity of antimicrobials against Pseudomonas aeruginosa, Achromobacter xylosoxidans and Stenotrophomonas maltophilia keratitis isolates. Br J Ophthalmol. 2018 May;102 (5) :708-712.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Citation 01

Antimicrob Agents Chemother. 2023 Jun 15;67 (6) :e0160322.|Microbiol Spectr. 2023 Feb 14;11 (1) :e0303822.|Microbiol Spectr. 2023 Jun 15;11 (3) :e0069223.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|Molecules. 2025 Mar 9;30 (6) :1224.