Fesomersen

Fesomersen is an antisense oligonucleotide designed to inhibit the production of Factor XI.

Product Specifications

CAS Number

[2380135-03-3]

Product Name Alternative

ION-957943 (free acid) ; BAY-3563450; IONIS-FXI-LRx

UNSPSC

12352208

Target

Others

Type

Oligonucleotides

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fesomersen.html

Solubility

10 mM in H2O

Smiles

[Fesomersen]

Molecular Formula

C296H434N82O156P20S13

Molecular Weight

8673.49

References & Citations

[1]Gómez-Outes A, Suárez-Gea ML, Pérez-Cabeza AI, García-Pinilla JM. Pharmacotherapy for stroke prevention in nonvalvular atrial fibrillation: current strategies and future directions. Expert Opin Pharmacother. 2022;23 (17) :1941-1955.|[2]Fredenburgh JC, Weitz JI. News at XI: Moving Beyond Factor Xa Inhibitors [published online ahead of print, 2023 Apr 26]. J Thromb Haemost. 2023; S1538-7836 (23) 00343-4. doi:10.1016/j.jtha.2023.04.021