Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Donidalorsen (sodium)

Donidalorsen (sodium) is an antisense oligonucleotide designed to reduce the production of prekallikrein (PKK) . PKK plays an important role in the activation of inflammatory mediators associated with acute attacks of Hereditary angioedema (HAE) .

Product Specifications

CAS Number

2304701-45-7

Product Name Alternative

ISIS-721744; IONIS-PKK-LRX

UNSPSC

12352208

Target

Kallikrein

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/donidalorsen-sodium.html

Purity

95.90

Solubility

10 mM in H2O

Smiles

[Donidalorsen(sodium)]

Molecular Formula

C296H415N83Na20O151P20S15

Molecular Weight

8672.6 (free acid)

References & Citations

[1]Fijen LM, Riedl MA, Bordone L, et al. Inhibition of Prekallikrein for Hereditary Angioedema. N Engl J Med. 2022;386 (11) :1026-1033. |[2]Valerieva A, Longhurst HJ. Treatment of hereditary angioedema-single or multiple pathways to the rescue. Front Allergy. 2022;3:952233.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PABPN1 Rabbit Monoclonal Antibody [Clone ID: R02-8B1]
TA384922 100 µL

PABPN1 Rabbit Monoclonal Antibody [Clone ID: R02-8B1]

Sign In for Pricing
View Details
SOX9 / SRY-box 9 (SOX9/2387), CF488A conjugate, 0.1mg/mL
BNC882387-100 1x 100 µL

SOX9 / SRY-box 9 (SOX9/2387), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
2-Fluoroiodobenzene
TRC-F591990-25G 25 g

2-Fluoroiodobenzene

Sign In for Pricing
View Details
Retinol Binding Protein-1 (RBP1) (rRBP1/872), CF405S conjugate, 0.1mg/mL
BNC043603-500 1x 500 µL

Retinol Binding Protein-1 (RBP1) (rRBP1/872), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG
135000-00-50.500MG 500 mg

Ɑ-Hydroxy-ω-Squaric Acid Ester Amido PEG

Sign In for Pricing
View Details
Progesterone Receptor (PR484), CF405S conjugate, 0.1mg/mL
BNC040484-500 1x 500 µL

Progesterone Receptor (PR484), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details