Cofirasersen (sodium)
Cofirasersen sodium is designed to reduce the expression of ENaC in the lung. ENaC is a sodium transport channel and believed to be hyperactive in cystic fibrosis, which is caused by mutations in the cystic fibrosis transmembrane regulator gene.
Product Specifications
Product Name Alternative
ION-827359 (sodium)
UNSPSC
12352208
Target
Sodium Channel
Type
Oligonucleotides
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cofirasersen-sodium.html
Solubility
10 mM in H2O
Smiles
[Cofirasersen(sodium)]
Molecular Formula
C172H202N57Na16O88P15S15
Molecular Weight
5437.55 (free acid)
References & Citations
[1]WHO Drug Information, Vol. 34, No. 3, 2020
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
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