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Cofirasersen (sodium)

Cofirasersen sodium is designed to reduce the expression of ENaC in the lung. ENaC is a sodium transport channel and believed to be hyperactive in cystic fibrosis, which is caused by mutations in the cystic fibrosis transmembrane regulator gene.

Product Specifications

Product Name Alternative

ION-827359 (sodium)

UNSPSC

12352208

Target

Sodium Channel

Type

Oligonucleotides

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cofirasersen-sodium.html

Solubility

10 mM in H2O

Smiles

[Cofirasersen(sodium)]

Molecular Formula

C172H202N57Na16O88P15S15

Molecular Weight

5437.55 (free acid)

References & Citations

[1]WHO Drug Information, Vol. 34, No. 3, 2020

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

Frequently Asked Questions

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