Cyclo (Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc)

Cyclo (Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc) provides an avenue for developing a nonhormonal male contraceptive by blocking of GRTH/DDX25 phosphorylation.

Product Specifications

UNSPSC

12352209

Target

DNA/RNA Synthesis

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cyclo-phe-ala-gly-arg-arg-arg-gly-aeeac.html

Solubility

10 mM in DMSO

Smiles

NC(NCCC[C@H](NC([C@H](CCCNC(N)=N)NC(CNC([C@H](C)NC([C@@H](NC(COCCOCCNC(CN1)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)C(N[C@@H](CCCNC(N)=N)C1=O)=O)=N

Molecular Formula

C40H67N17O10

Molecular Weight

946.07

References & Citations

[1]Raju M, et al. Blockade of GRTH/DDX25 Phosphorylation by Cyclic Peptides Provides an Avenue for Developing a Nonhormonal Male Contraceptive. J Med Chem. 2021 Oct 14;64 (19) :14715-14727.