Cyclo (Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc)
Cyclo (Phe-Ala-Gly-Arg-Arg-Arg-Gly-AEEAc) provides an avenue for developing a nonhormonal male contraceptive by blocking of GRTH/DDX25 phosphorylation.
Product Specifications
UNSPSC
12352209
Target
DNA/RNA Synthesis
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cyclo-phe-ala-gly-arg-arg-arg-gly-aeeac.html
Solubility
10 mM in DMSO
Smiles
NC(NCCC[C@H](NC([C@H](CCCNC(N)=N)NC(CNC([C@H](C)NC([C@@H](NC(COCCOCCNC(CN1)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)C(N[C@@H](CCCNC(N)=N)C1=O)=O)=N
Molecular Formula
C40H67N17O10
Molecular Weight
946.07
References & Citations
[1]Raju M, et al. Blockade of GRTH/DDX25 Phosphorylation by Cyclic Peptides Provides an Avenue for Developing a Nonhormonal Male Contraceptive. J Med Chem. 2021 Oct 14;64 (19) :14715-14727.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6370319-01 0.1 mL
ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6) (PE)
Ask
View Details MBS6370319-02 5x 0.1 mL
ARHGEF6 (COOL2, KIAA0006, PIXA, Rho Guanine Nucleotide Exchange Factor 6, Alpha-Pix, COOL-2, PAK-interacting Exchange Factor alpha, Rac/Cdc42 Guanine Nucleotide Exchange Factor 6) (PE)
Ask
View Details