IMD-catechol
Product Specifications
UNSPSC Description
IMD-catechol is a novel imidazoquinolinone-NF-κB immunomodulator dimer that improves efficacy in a CT26 mouse colon carcinoma tumor model while eliciting minimal adjuvant toxicity.
Target Antigen
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/imd-catechol.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(C=CC=C2)=C2C3=C1N=C(CCCC)N3CC4=CC=C(CNC(NCCC5=CC(O)=C(O)C=C5)=O)C=C4
Molecular Weight
538.64
References & Citations
[1]Kimani FW, et al. Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NF-κB Modulators. ACS Med Chem Lett. 2021 Aug 26;12(9):1441-1448.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139716/IMD-catechol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139716/
Clinical Information
No Development Reported
CAS Number
2928463-39-0
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