Glucocorticoids receptor agonist 2
Glucocorticoids receptor agonist 2 is a potent anti-inflammatory, arylpyrazole-based glucocorticoid receptor agonist that does not impair insulin secretion.
Product Specifications
CAS Number
614761-20-5
UNSPSC
12352005
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/glucocorticoids-receptor-agonist-2.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@@]1([H])CCCC2=CC3=C(C[C@@]21C)C=NN3C4=CC=C(F)C=C4)C5=CC=CC=C5
Molecular Formula
C25H25FN2O
Molecular Weight
388.48
References & Citations
[1]Kennedy BJ, et al. Potent Anti-Inflammatory, Arylpyrazole-Based Glucocorticoid Receptor Agonists That Do Not Impair Insulin Secretion. ACS Med Chem Lett. 2021 Sep 15;12 (10) :1568-1577.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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