NMDA receptor antagonist-3
NMDA receptor antagonist-3, a NMDA receptor antagonist, stands out with a remarkable percentage of recovery (40.0%, at 100 μM) and safe toxicological profile in SH-SY5Y and human adipose mesenchymal stem cells.
Product Specifications
CAS Number
[2762181-52-0]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nmda-receptor-antagonist-3.html
Solubility
10 mM in DMSO
Smiles
O=C(CN)N1[C@@H](C2)CC[C@@H]2[C@@]1([H])C(N[C@H](C(O)=O)CC(O)=O)=O
Molecular Formula
C13H19N3O6
Molecular Weight
313.31
References & Citations
[1]Sampaio-Dias IE, et al. Design, Synthesis, and Biological Evaluation of Hybrid Glypromate Analogues Using 2-Azanorbornane as a Prolyl and Pipecolyl Surrogate. ACS Chem Neurosci. 2021 Oct 6;12 (19) :3615-3624.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Curated Selection
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